Spontaneous and genetically engineered animal models: use in preclinical cancer drug development
作者： K Hansen , C Khanna
DOI: 10.1016/J.EJCA.2003.11.031
关键词: Genetically engineered 、 Drug 、 Cancer drugs 、 Genetically modified organism 、 Transplantation 、 Biology 、 Cancer 、 Transgene 、 Pharmacology 、 Bioinformatics 、 Pre-clinical development
摘要: The preclinical development of anticancer drugs has been based primarily on the transplantation of murine or human cancers into mice. Alternatives to these transplantation models are …
elsevier.com
sci-hub.se 参考文章(146)
R T Bronson, Variation in age at death of dogs of different sexes and breeds. American Journal of Veterinary Research. ,vol. 43, pp. 2057- 2059 ,(1982)
Enrique Gómez-La-Hoz, Enrique Gómez-La-Hoz, Roman Halter, Miguel Beato, Guntram Suske, Andrea Sandmöller, Hermann Josef Gröne, Dieter Paul, The uteroglobin promoter targets expression of the SV40 T antigen to a variety of secretory epithelial cells in transgenic mice Oncogene. ,vol. 9, pp. 2805- 2815 ,(1994)
Stephan Metz, Heike E Daldrup-Link, Thomas Richter, Christoph Räth, Wolfgang Ebert, Marcus Settles, Ernst J Rummeny, Thomas M Link, Morand Piert, Detection and Quantification of Breast Tumor Necrosis with MR Imaging Academic Radiology. ,vol. 10, pp. 484- 490 ,(2003) , 10.1016/S1076-6332(03)80056-9
E Teske, G R Rutteman, W Misdorp, R van Noort, T S vd Ingh, Liposome-encapsulated muramyl tripeptide phosphatidylethanolamine (L-MTP-PE): a randomized clinical trial in dogs with mammary carcinoma. Anticancer Research. ,vol. 18, pp. 1015- 1019 ,(1998)
R Storb, E D Thomas, W C Ladiges, Canine models of bone marrow transplantation. Laboratory Animal Science. ,vol. 40, pp. 11- 15 ,(1990)
F.E. Diehn, N.G. Costouros, M.S. Miller, A.L. Feldman, H.R. Alexander, K.C.P. Li, S.K. Libutti, Noninvasive Fluorescent Imaging Reliably Estimates Biomass In Vivo BioTechniques. ,vol. 33, pp. 1250- 1255 ,(2002) , 10.2144/02336ST02
Karen Rickard-Dickson, Patrick Clarke, Jeffrey Mann, F. James Primus, F. James Primus, Jean F. Simpson, Mice Transgenic for Human Carcinoembryonic Antigen as a Model for Immunotherapy Cancer Research. ,vol. 58, pp. 1469- 1477 ,(1998)
Raju Kucherlapati, Heidi Hörig, Winfried Edelmann, Howard L. Kaufman, Akiva Marcus, Li Long, Alberto Wainstein, Doron Kahn, Sandeep Soni, A new mouse model for evaluating the immunotherapy of human colorectal cancer Cancer Research. ,vol. 61, pp. 8520- 8526 ,(2001)
Ronald A. Lubet, Elizabeth Kastens, Yian Wang, Zhongqiu Zhang, Ming You, Mice with alterations in both p53 and Ink4a/Arf display a striking increase in lung tumor multiplicity and progression: differential chemopreventive effect of budesonide in wild-type and mutant A/J mice. Cancer Research. ,vol. 63, pp. 4389- 4395 ,(2003)
Priester Wa, McKay Fw, The occurrence of tumors in domestic animals. National Cancer Institute monograph. pp. 1- 210 ,(1980)