Spontaneous Occurrence of Brain Tumors in Animals: Opportunities as Preclinical Model Systems
作者： Simon R. Platt
DOI: 10.1007/978-1-60327-553-8_13
关键词:
摘要: Naturally occurring neoplasia of the nervous system has been documented in many species addition to humans, which include dogs, cats, mice, and even zebrafish. Some tumors these share features including histopathological appearance, neuroimaging characteristics, tumor genetics, molecular targets, biological behavior. Based on such similarities, studying CNS dogs mice genetics neuronal Drosophila zebrafish suggested as a valuable pursuit field cancer research can aid following areas: identification cancer-associated genes, environmental risk factors, biology, progression development novel therapeutics. This chapter reviews current knowledge types spontaneously affect Drosophila, demonstrates potential utility naturally models research.
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Gavin Pr, Wendling Lr, Miller Dl, Kraft Sl, Canine spontaneous brain tumors--a large animal model for BNCT. Strahlentherapie Und Onkologie. ,vol. 165, pp. 225- ,(1989)
G W Niebauer, B L Dayrell-Hart, J Speciale, Evaluation of craniotomy in dogs and cats. Javma-journal of The American Veterinary Medical Association. ,vol. 198, pp. 89- 95 ,(1991)
R. Skillen, D. B. Freshwater, M. Ingram, G. B. Techy, C. H. Shelden, D. B. Jacques, Adoptive immunotherapy of brain tumors in dogs. Veterinary Medicine Report. ,vol. 2, pp. 398- 402 ,(1990)
J. R. Fike, Richard A Lecouteur, C. M. Pflugfelder, J. M. Turrel, J. K. Borcich, Radiotherapy of brain tumors in dogs. Javma-journal of The American Veterinary Medical Association. ,vol. 184, pp. 82- 86 ,(1984)
K Hansen, C Khanna, Spontaneous and genetically engineered animal models: use in preclinical cancer drug development European Journal of Cancer. ,vol. 40, pp. 858- 880 ,(2004) , 10.1016/J.EJCA.2003.11.031
Rolf F. Barth, Rat brain tumor models in experimental neuro-oncology:The 9L, C6, T9, F98, RG2 (D74), RT-2 and CNS-1 Gliomas Journal of Neuro-oncology. ,vol. 36, pp. 91- 102 ,(1998) , 10.1023/A:1005805203044
N. G. Rainov, S. Koch, M. Sena-Esteves, M. E. Berens, Characterization of a Canine Glioma Cell Line As Related to Established Experimental Brain Tumor Models Journal of Neuropathology & Experimental Neurology. ,vol. 59, pp. 607- 613 ,(2000) , 10.1093/JNEN/59.7.607
Patrick R. Gavin, Susan L. Kraft, René Huiskamp, Jeffrey A. Coderre, A review: CNS effects and normal tissue tolerance in dogs Journal of Neuro-oncology. ,vol. 33, pp. 71- 80 ,(1997) , 10.1023/A:1005773331737
A. Koestner, Histological Classification of Tumors of the Nervous System of Domestic Animals ,(1999)
G.J. Pilkington, J.L. Darling, P.L. Lantos, D.G.T. Thomas, Tumorigenicity of cell lines (VMDk) derived from a spontaneous murine astrocytoma Journal of the Neurological Sciences. ,vol. 71, pp. 145- 164 ,(1985) , 10.1016/0022-510X(85)90056-5