miR-181 targets multiple Bcl-2 family members and influences apoptosis and mitochondrial function in astrocytes.

作者: Yi-Bing Ouyang , Yu Lu , Sibiao Yue , Rona G. Giffard

DOI: 10.1016/J.MITO.2011.09.001

关键词: Cancer researchRegulation of gene expressionBcl-2 familyApoptosisAstrocytemicroRNAProtein familyMitochondrionMyeloid Cell Leukemia Sequence 1 ProteinBiologyCell biology

摘要: Mitochondria are central to the execution of apoptosis, and the Bcl-2 protein family of pro- and anti-apoptotic proteins interacts with mitochondria to regulate apoptosis. Using …

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