Intrahepatic cholestasis of pregnancy: perinatal outcome associated with expectant management.
作者： Owaidah M. Alsulyman , Joseph G. Ouzounian , Mary Ames-Castro , T.Murphy Goodwin
DOI: 10.1016/S0002-9378(96)80031-7
关键词: Prenatal care 、 Cholestasis of pregnancy 、 Gestational age 、 Medicine 、 Meconium 、 Cholestasis 、 Birth weight 、 Pregnancy 、 Obstetrics 、 Gestation
摘要: OBJECTIVE: Our goal was to compare the pregnancy outcomes of patients with intrahepatic cholestasis managed expectantly antepartum testing those other who were followed up a similar scheme. STUDY DESIGN: Cases monitored at our institution over 7-year period reviewed. Their compared control same scheme for history stillbirth. Both groups had least weekly nonstress tests and amniotic fluid assessment until spontaneous labor or delivery standard obstetric indications. RESULTS: Seventy-nine analyzed in each group. The two did not differ respect mean gestational age (38.5 vs 38.8 weeks), birth weight (3216 3277 gm) incidence preterm (14% 7.6%). Abnormal prompting more common group (25% 7.6%, p < 0.05). risk meconium passage higher (44.3% Two fetal deaths occurred 36 37 weeks' gestation within 5 days normal results testing. Thick appropriate noted both infants. No gross anomalies found either infant. CONCLUSION: Intrahepatic is associated adverse perinatal outcome predicted by conventional surveillance. (Am J Obstet Gynecol 1996;175:957-60.)
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