Interlaboratory reproducibility of the immunocytochemical assessment of oestrogen and progesterone receptors and proliferative activity in fine needle aspiration of breast cancer.

作者： M. CONFORTINI , F. CAROZZI , L. BOZZOLA , G. MICCINESI , F. MIRRI

DOI: 10.1046/J.1365-2303.2002.00374.X

关键词: Medicine 、 Fine-needle aspiration 、 Receptor 、 Breast cancer 、 Cancer 、 Pathology 、 Interlaboratory reproducibility 、 Immunocytochemistry

摘要: Interlaboratory reproducibility of the immunocytochemical assessment oestrogen and progesterone receptors proliferative activity in fine needle aspiration breast cancer The purpose this study was to establish interlaboratory analysis (ER) (PR) expression Mib1 growth fraction on (FNA) smears. A set 44 immunostained slides for ER, PR were randomly selected from archives Center Study Prevention Cancer (CSPO) Florence, Italy, submitted reading 6 Italian laboratories. The generalized kappa statistic used as an indicator agreement among six good correlation ER evident. For results showed some discrepancies. In addition adequate standardization procedures, these data confirm that reliability immunocytochemistry is strictly linked accurate results.

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Interlaboratory reproducibility of the immunocytochemical assessment of oestrogen and progesterone receptors and proliferative activity in fine needle aspiration of breast cancer.

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Interlaboratory reproducibility of the immunocytochemical assessment of oestrogen and progesterone receptors and proliferative activity in fine needle aspiration of breast cancer.

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