Receptor that leaves a sour taste in the mouth

作者: Shinya Ugawa , Yuki Minami , Wei Guo , Yoshitsugu Saishin , Koichi Takatsuji

DOI: 10.1038/26882

关键词: GPR120BiochemistryTasteReceptorTaste receptorBiologyTAS1R3TAS1R2G proteinTransduction (physiology)

摘要: The ability to detect taste stimuli results from the activation of receptors located in taste-bud cells. There are several gustatory transduction mechanisms, involving membrane receptors, guanine-nucleotide-binding proteins (G proteins), second messengers and ion channels1, but genes encoding have not yet been identified. Here we identify a complementary DNA that encodes receptor for sour tastes.

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