Development of Triprolidine-Hydrochloride-Loaded pH-Sensitive Poly(Acrylamide-co-Acrylamidoglycolic Acid) Co-Polymer Microspheres: In Vitro Release Studies

作者: B. Mallikarjuna , K. Madhusudhana Rao , C. Venkata Prasad , K. Chowdoji Rao , M. C. S. Subha

DOI: 10.1163/138577211X587645

关键词: Controlled releaseHydrochlorideDrug deliveryIn vitroCopolymerEmulsion polymerizationAcrylamideTriprolidineMaterials scienceNuclear chemistryPolymer chemistry

摘要: Poly(acrylamide-co-acrylamidoglycolic acid) co-polymeric microspheres cross-linked with N,N-methylene bisacrylamide have been prepared by free radical emulsion polymerization using varying amounts ...

参考文章(28)
F. Estelle R. Simons, Advances in H1-Antihistamines The New England Journal of Medicine. ,vol. 351, pp. 2203- 2217 ,(2004) , 10.1056/NEJMRA033121
Sung Wan Kim, You Han Bae, Teruo Okano, Hydrogels: swelling, drug loading, and release. Pharmaceutical Research. ,vol. 9, pp. 283- 290 ,(1992) , 10.1023/A:1015887213431
M SAIRAM, V BABU, B NAIDU, T AMINABHAVI, Encapsulation efficiency and controlled release characteristics of crosslinked polyacrylamide particles. International Journal of Pharmaceutics. ,vol. 320, pp. 131- 136 ,(2006) , 10.1016/J.IJPHARM.2006.05.001
Richard W. Korsmeyer, Nikolaos A. Peppas, Effect of the morphology of hydrophilic polymeric matrices on the diffusion and release of water soluble drugs Journal of Membrane Science. ,vol. 9, pp. 211- 227 ,(1981) , 10.1016/S0376-7388(00)80265-3
Ajit P. Rokhade, Sunil A. Agnihotri, Sangamesh A. Patil, Nadagouda N. Mallikarjuna, Padmakar V. Kulkarni, Tejraj M. Aminabhavi, Semi-interpenetrating polymer network microspheres of gelatin and sodium carboxymethyl cellulose for controlled release of ketorolac tromethamine Carbohydrate Polymers. ,vol. 65, pp. 243- 252 ,(2006) , 10.1016/J.CARBPOL.2006.01.013
K. Langer, C. Marburger, A. Berthold, J. Kreuter, F. Stieneker, Methylmethacrylate sulfopropylmethacrylate copolymer nanoparticles for drug delivery. Part I: Preparation and physicochemical characterization International Journal of Pharmaceutics. ,vol. 137, pp. 67- 74 ,(1996) , 10.1016/0378-5173(96)89589-5
V. Ramesh Babu, K. Mallikarjuna Reddy, M. Sairam, M. C. S. Subha, N. N. Mallikarjuna, P. V. Kulkarni, T. M. Aminabhavi, Preparation and characterization of atenolol-loaded cellulose acetate butyrate-poly(vinyl pyrrolidone) blend microspheres: in vitro release studies Designed Monomers and Polymers. ,vol. 10, pp. 155- 165 ,(2007) , 10.1163/156855507780378276
Olga Garcı́a, M.Dolores Blanco, Juan Antonio Martı́n, José M Teijón, 5-Fluorouracil trapping in poly(2-hydroxyethyl methacrylate-co-acrylamide) hydrogels: in vitro drug delivery studies European Polymer Journal. ,vol. 36, pp. 111- 122 ,(2000) , 10.1016/S0014-3057(99)00037-3