Comparative analyses of humoral and cell-mediated immune responses upon vaccination with different commercially available single-dose porcine circovirus type 2 vaccines
作者： Hwi Won Seo , Jeehoon Lee , Kiwon Han , Changhoon Park , Chanhee Chae
DOI: 10.1016/J.RVSC.2014.04.007
关键词: Porcine circovirus associated disease 、 Immunity 、 Antibody 、 Porcine circovirus 、 Viral Vaccine 、 Biology 、 Circovirus 、 Immune system 、 Vaccination 、 Virology 、 Immunology
摘要: The objective of this study was to compare the induction humoral and cell-mediated immune responses by four commercially available single-dose porcine circovirus type 2 (PCV-2) vaccines. A total 50 3-week-old piglets were assigned five groups (10 pigs per group). Four commercial PCV-2 vaccines administered according manufacturer's instructions observed for 154 days post vaccination (dpv). Inactivated chimeric PCV-1-2 induced higher levels PCV-2-specific neutralizing antibodies (NA) interferon-γ-secreting cells (IFN-γ-SC) in than did other three proportions CD4(+) significantly animals vaccinated with inactivated two subunit To our knowledge, is first comparison immunity under same conditions. results demonstrated quantitative differences following vaccination.
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