作者: Bernhard Kutscher , Gerald McMahon , Harald App , Heinz Weinberger
DOI:
关键词: Biochemistry 、 Kinase 、 Serine/threonine-specific protein kinase 、 Receptor protein serine/threonine kinase 、 Serine 、 Protein kinase C 、 Serine threonine protein kinase 、 Biology 、 Threonine 、 Protein kinase A
摘要: The present invention is directed in part towards methods of modulating the function serine/threonine protein kinases with azabenzimidazole-based compounds. incorporate cells that express a kinase, such as RAF. In addition, describes preventing and treating kinase-related abnormal conditions organisms compound identified by invention. Furthermore, pertains to azabenzimidazole compounds pharmaceutical compositions comprising these