Indolinone compounds for the treatment of disease

作者: Li Sun , Gerald Mcmahon , Peng Cho Tang

DOI:

关键词: DiseaseBiologyBiochemistrySignal transductionCell growthCell biologyKinaseTyrosineOrganic molecules

摘要: The present invention REFERS TO organic molecules able to modulate signal transduction kinase tyrosine regulate, and / or inhibit cell proliferation FREAK.

参考文章(16)
Baut Guillaume Le, Pierre Renard, de la Faverie Jean-François Renaud, Gérard Adam, Daniel-Henri Caignard, Jean-Guy Bizot-Espiard, Marie Renée Nourisson, 3-(Hydroxybenzylidenyl)-indoline-2-ones and pharmaceutical compositions containing them ,(1993)
Jagadish C. Sircar, Ila Sircar, Imidazole with angiotensin II antagonist properties ,(1992)
Susumu Nakanishi, Oxindole peptide antagonists ,(1991)
Antonio Longo, Franco Buzzetti, Maristella Colombo, Methylen-oxindole derivatives and process for their preparation ,(1992)
I. W. Elliott, P. Rivers, Reduction of Some Oxindolylidene Derivatives to 3-Substituted Oxindoles by Sodium Borohydride1 The Journal of Organic Chemistry. ,vol. 29, pp. 2438- 2440 ,(1964) , 10.1021/JO01031A502
Carl T. Bahnr, Brotherton David H., Harold Kinder, William Rich, Stuart L. Watson, John Zirkle, 6-(Dimethylamino)chrysene and other analogs of 4-(4-dimethylamino)stilbene Journal of Medicinal Chemistry. ,vol. 12, pp. 722- 722 ,(1969) , 10.1021/JM00304A051
Edward A. Nodiff, Keiichi Tanabe, Christoph Seyfried, Shin Matsuura, Yasuaki Kondo, Eugene H. Chen, Mahesh P. Tyagi, Antimalarial phenathrene amino alcohols. 1. Fluorine-containing 3- and 6-substituted 9-phenanthrenemethanols Journal of Medicinal Chemistry. ,vol. 14, pp. 921- 925 ,(1971) , 10.1021/JM00292A007
Roy W. Daisley, John Walker, Thin-layer chromatographic separation of some substituted 3-benzylidene-indol-2(3H)-ones Journal of Chromatography A. ,vol. 100, pp. 240- 242 ,(1974) , 10.1016/S0021-9673(00)86069-0
Andreina Corsico Coda, Anna Gamba Invernizzi, Pier Paolo Righetti, Gianfranco Tacconi, Giuseppina Gatti, (Z)- and (E)-Arylidene-1,3-dihydroindol-2-ones: configuration, conformation, and infrared carbonyl stretching frequencies Journal of The Chemical Society-perkin Transactions 1. ,vol. 15, pp. 615- 619 ,(1984) , 10.1039/P29840000615