Hematopoietic stem cell chimerism to treat autoimmune disease

作者: Suzanne T. Ildstad

DOI:

关键词: Hematopoietic stem cellMixed chimerismImmunologyHost factorsAutoimmune diseaseBiology

摘要: The primary focus of this the present invention is to disclose a minimal conditioning approach establish mixed chimerism induce tolerance in recipients having autoimmune disease. Engraftment multifactorial. Both donor and host factors influence outcome then defining recipient that resist engraftment. Chimerisms with minimum morbidity can be achieved, thus allowing for prevention treatment

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