Non-lethal methods for conditioning a recipient for bone marrow transplantation
作者： Suzanne T. Ildstad
DOI:
关键词: Total body irradiation 、 Autoimmunity 、 Cell 、 Immunology 、 Haematopoiesis 、 Bone marrow 、 Cytotoxic T cell 、 Solid organ 、 Biology 、 Antibody
摘要: The present invention relates to non-lethal methods of conditioning a recipient for bone marrow transplantation. In particular, it the use nonlethal doses total body irradiation, lymphoid irradiation cell type-specific antibodies, especially antibodies directed stromal markers, cytotoxic drugs, or combination thereof. have wide range applications, including, but not limited to, an individual hematopoietic reconstitution by transplantation treatment hematologic malignancies, disorders, autoimmunity, infectious diseases such as acquired immunodeficiency syndrome, and engraftment cells induce tolerance solid organ, tissue cellular
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