A combination therapy for a stable and long term engraftment

摘要: A method of treating a subject in need non-syngeneic cell or tissue graft is disclosed. The comprising: (a) transplanting into dose T depleted immature hematopoietic cells, wherein the cells comprise less than 5 x 105 CD3+ per kilogram body weight subject, and comprises at least about 106 CD34+ subject; subsequently (b) administering to therapeutically effective amount cyclophosphamide, 25-200 mg weight, thereby subject.