Novel cell signaling polypeptides and nucleic acids
作者： Paul Diaz , Rosamaria Ruggieri , Marinella Callow
DOI:
关键词: Homologous chromosome 、 Apoptosis 、 Kinase activity 、 Cell biology 、 Biochemistry 、 Cell signaling 、 Signal transduction 、 Cell survival 、 Nucleic acid 、 Transcription (biology) 、 Biology
摘要: The present invention relates to an isolated SRK polypeptide, biologically-active polypeptide fragments thereof, and nucleic acids which code for it. This has various activities in regulating cell signaling signal transduction pathways, including, e.g., a protein kinase activity; autophosphorylating survival promoting HAX-1 binding apoptosis suppression MAPKK stimulatory transcription modulatory activity, SRK-specific immunogenic activity. all aspects of SRK, or homologs including assays modulators, activators, ligands, etc. also cytolic soluble produces when expressed cells.
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