Cancer-associated fibroblasts modulate growth factor signaling and extracellular matrix remodeling to regulate tumor metastasis
作者： Begum Erdogan , Donna J. Webb
DOI: 10.1042/BST20160387
关键词: Biology 、 Cancer cell 、 Tumor microenvironment 、 Metastasis 、 Extracellular matrix 、 Cancer 、 Stromal cell 、 Cancer research 、 Cell migration 、 Cancer-Associated Fibroblasts
摘要: … the myosin-II (MyoII) inhibitor blebbistatin significantly reduced the invasion of these foci, whereas treatment with the broad MMP inhibitor GM6001 did not perturb the matrix remodeling …
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