Heart Failure due to Ischaemic Heart Disease: Epidemiology, Pathophysiology and Progression

作者: John G.F. Cleland , James McGowan

DOI: 10.1097/00005344-199906003-00003

关键词: DigoxinMyocardial infarctionIschemiaIntensive care medicineHeart failureVascular diseaseSurgeryHeart diseaseEpidemiologyAmlodipineMedicinePharmacologyCardiology and Cardiovascular Medicine

摘要: Ischaemic heart disease is the most common underlying cause of failure in industrialised countries. Its manifestations are protean with myocardial infarction being only one important facet. The prognosis patients due to ischaemic also appears be worse than that associated many other aetiologies. presence may influence both efficacy and choice treatment. Agents such as digoxin amlodipine appear less effective while ACE inhibitors beta-blockers or more disease. Many have expressed an opinion about how coronary should managed patient supported by little no evidence. There major theoretical practical concerns use anti-coagulant, anti-platelet statin therapy well benefits. Only randomised controlled trials will resolve these issues. same said revascularisation. Fortunately addressing all areas under way. This put management on a firm evidence-based footing.

参考文章(85)
Marc A Pfeffer, Eugene Braunwald, Lemuel A Moyé, Lofty Basta, Edward J Brown Jr, Thomas E Cuddy, Barry R Davis, Edward M Geltman, Steven Goldman, Greg C Flaker, Marc Klein, Gervasio A Lamas, Milton Packer, Jacques Rouleau, Jean L Rouleau, John Rutherford, John H Wertheimer, C Morton Hawkins, None, EFFECT OF CAPTOPRIL ON MORTALITY AND MORBIDITY IN PATIENTS WITH LEFT VENTRICULAR DYSFUNCTION AFTER MYOCARDIAL INFARCTION. RESULTS OF THE SURVIVAL AND VENTRICULAR ENLARGEMENT TRIAL The New England Journal of Medicine. ,vol. 327, pp. 669- 677 ,(1992) , 10.1056/NEJM199209033271001
Milton Packer, Christopher M. O'Connor, Jalal K. Ghali, Milton L. Pressler, Peter E. Carson, Robert N. Belkin, Alan B. Miller, Gerald W. Neuberg, David Frid, John H. Wertheimer, Anne B. Cropp, David L. DeMets, Effect of Amlodipine on Morbidity and Mortality in Severe Chronic Heart Failure The New England Journal of Medicine. ,vol. 335, pp. 1107- 1114 ,(1996) , 10.1056/NEJM199610103351504
Lars Køber, Christian Torp-Pedersen, Jan E. Carlsen, Henning Bagger, Per Eliasen, Kjeld Lyngborg, Jørgen Videbæk, David S. Cole, Laurent Auclert, Nancy C. Pauly, Etienne Aliot, Stig Persson, A. John Camm, A Clinical Trial of the Angiotensin-Converting–Enzyme Inhibitor Trandolapril in Patients with Left Ventricular Dysfunction after Myocardial Infarction The New England Journal of Medicine. ,vol. 333, pp. 1670- 1676 ,(1995) , 10.1056/NEJM199512213332503
Milton Packer, Michael R. Bristow, Jay N. Cohn, Wilson S. Colucci, Michael B. Fowler, Edward M. Gilbert, Neil H. Shusterman, The Effect of Carvedilol on Morbidity and Mortality in Patients with Chronic Heart Failure The New England Journal of Medicine. ,vol. 334, pp. 1349- 1355 ,(1996) , 10.1056/NEJM199605233342101
Milton Packer, Mihai Gheorghiade, James B Young, Peter J Costantini, Kirkwood F Adams, Robert J Cody, L Kent Smith, Lucy Van Voorhees, Lynn A Gourley, M King Jolly, None, WITHDRAWAL OF DIGOXIN FROM PATIENTS WITH CHRONIC HEART FAILURE TREATED WITH ANGIOTENSIN CONVERTING ENZYME INHIBITORS Cardiovascular reviews and reports. ,vol. 329, pp. 1- 7 ,(2010) , 10.1056/NEJM199307013290101
Steven N. Singh, Ross D. Fletcher, Susan Gross Fisher, Bramah N. Singh, H. Daniel Lewis, Prakash C. Deedwania, Barry M. Massie, Cindy Colling, Diane Lazzeri, Amiodarone in Patients with Congestive Heart Failure and Asymptomatic Ventricular Arrhythmia New England Journal of Medicine. ,vol. 333, pp. 77- 82 ,(1995) , 10.1056/NEJM199507133330201