Optimization of a polarized source for in vivo x-ray fluorescence analysis of platinum and other heavy metals.

作者: D G Lewis

DOI: 10.1088/0031-9155/39/1/012

关键词: CollimatorScatteringOpticsPolarizerPhysicsBeam diameterPhoton energyPhotonMonte Carlo methodPolarization (waves)

摘要: The Monte Carlo method was used to optimize a polarized photon source for the X-ray fluorescence analysis of platinum and other heavy metals in vivo. consisted 140 kVp, 25 mA tube with photons plane-polarized by 90 degrees scattering. use results significant reduction background when fluorescent radiation is measured along direction polarization. A computer programme written simulate production interaction order determine optimal polarizing material dimensions, together beam width geometrical arrangement source, polarizer collimators. Calculated energy distributions are compared experimental data test validity model. best configuration polarization system vivo 20 mm Cu block secondary collimator subtending 0.1 radian angle at polarizer.

参考文章(12)
Richard W. Ryon, John D. Zahrt, Improved x-ray fluorescence capabilities by excitation with high intensity polarized x-rays Advances in x-ray analysis. ,vol. 22, pp. 453- 460 ,(1978) , 10.1154/S0376030800016827
Richard W. Ryon, John D. Zahrt, Peter Wobrauschek, Hannes Aiginger, The Use of Polarized X-Rays for Improved Detection Limits in Energy Dispersive X-Ray Spectrometry. Advances in x-ray analysis. ,vol. 25, pp. 63- 74 ,(1981) , 10.1154/S0376030800009538
J. H. Hubbell, Wm. J. Veigele, E. A. Briggs, R. T. Brown, D. T. Cromer, R. J. Howerton, Atomic form factors, incoherent scattering functions, and photon scattering cross sections Journal of Physical and Chemical Reference Data. ,vol. 4, pp. 471- 538 ,(1975) , 10.1063/1.555523
R Jonson, S Mattsson, B Unsgaard, A method for in vivo analysis of platinum after chemotherapy: with cisplatin Physics in Medicine and Biology. ,vol. 33, pp. 847- 857 ,(1988) , 10.1088/0031-9155/33/7/008
Leon Kaufman, Dale Shosa, David C. Camp, A High Intensity Source of Polarized X-Rays for Fluorescent Excitation Analysis (FEA) IEEE Transactions on Nuclear Science. ,vol. 24, pp. 525- 531 ,(1977) , 10.1109/TNS.1977.4328736
Alden N Bice, Monte Carlo PET simulations: effect of photon polarization on scatter estimates Physics in Medicine and Biology. ,vol. 37, pp. 1185- 1188 ,(1992) , 10.1088/0031-9155/37/5/013
A.L. Hanson, THE CALCULATION OF SCATTERING CROSS SECTIONS FOR POLARIZED X-RAYS * Nuclear Instruments & Methods in Physics Research Section A-accelerators Spectrometers Detectors and Associated Equipment. ,vol. 243, pp. 583- 598 ,(1986) , 10.1016/0168-9002(86)90999-X
R Birch, M Marshall, Computation of bremsstrahlung X-ray spectra and comparison with spectra measured with a Ge(Li) detector Physics in Medicine and Biology. ,vol. 24, pp. 505- 517 ,(1979) , 10.1088/0031-9155/24/3/002
Lellery Storm, Harvey I. Israel, Photon cross sections from 1 keV to 100 MeV for elements Z=1 to Z=100 Atomic Data and Nuclear Data Tables. ,vol. 7, pp. 565- 681 ,(1970) , 10.1016/S0092-640X(70)80017-1