Immobilization of Penicillium chrysogenum : spore growth on Celite

作者: T. Keshavarz , E. Walker , R. Eglin , G. Lilley , G. Holt

DOI: 10.1007/BF00263853

关键词: SporeBiomassMyceliumChromatographyChemistryGerminationSuspension (chemistry)PenicilliumAdsorptionPenicillium chrysogenum

摘要: Penicillium chrysogenum spores have been immobilized by adsorption on two grades of wet or dry diatomaceous earth particles, Chromosorb-W and Celite R-633. Almost 90% the were adsorbed within 2 h those remaining in suspension removed washing to minimise growth free mycelia. After germination biomass was almost independent spore loading particles whether not added particles. The obtained less than 5% biomass.

参考文章(10)
Alan Jones, Denise N. Wood, Theresa Razniewska, G. Maurice Gaucher, Leo A. Behie, Continuous production of penicillin-g by penicillium chrysogenum cells immobilized on celite biocatalyst support particles The Canadian Journal of Chemical Engineering. ,vol. 64, pp. 547- 552 ,(1986) , 10.1002/CJCE.5450640404
Kodzo Gbewonyo, Daniel I. C. Wang, Confining mycelial growth to porous microbeads: a novel technique to alter the morphology of non-newtonian mycelial cultures. Biotechnology and Bioengineering. ,vol. 25, pp. 967- 983 ,(1983) , 10.1002/BIT.260250407
Y. M. Deo, G. M. Gaucher, Semi-continuous production of the antibiotic patulin by immobilized cells of Penicillium urticae Biotechnology Letters. ,vol. 5, pp. 125- 130 ,(1983) , 10.1007/BF00132171
W. Mahmoud, H.J. Rehm, Morphological examination of immobilized Streptomyces aureofaciens during chlortetracycline fermentation Applied Microbiology and Biotechnology. ,vol. 23, pp. 305- 310 ,(1986) , 10.1007/BF00261934
Daniel I. C. Wang, Jürg Meier, Katsushisa Yokoyama, Penicillin fermentation in a 200-liter tower fermentor using cells confined to microbeads. Applied Biochemistry and Biotechnology. ,vol. 9, pp. 105- 116 ,(1984) , 10.1007/BF02798378
J. H. Kim, D. K. Oh, S. K. Park, Y. H. Park, D. A. Wallis, Production of penicillin in a fluidized-bed bioreactor using a carrier-supported mycelial growth. Biotechnology and Bioengineering. ,vol. 28, pp. 1838- 1844 ,(1986) , 10.1002/BIT.260281211
E. J. Arcuri, J. R. Nichols, T. S. Brix, V. G. Santamarina, B. C. Buckland, S. W. Drew, Thienamycin production by immobilized cells of Streptomyces cattleya in a bubble column. Biotechnology and Bioengineering. ,vol. 25, pp. 2399- 2411 ,(1983) , 10.1002/BIT.260251010