Impairment of cell-mediated immune responses in HTLV-I-associated myelopathy.

作者: Yasuo Kuroda , Hiroshi Takashima

DOI: 10.1016/0022-510X(90)90035-L

关键词: Htlv i associated myelopathyImmune systemImmunityLymphocytopeniaMyelopathyMedicineVirusImmunopathologyImmunologyLymphoproliferative response

摘要: Summary In order to assess in vivo cell-mediated immune functions HTLV-I-associated myelopathy (HAM), we immunized 18 HAM patients with dinitrochlorobenzene (DNCB). Of patients, the skin reaction DNCB was negative 15. All those 15 also showed anergy PPD-tuberculin and 9 of had a persistent lymphocytopenia (

参考文章(27)
Isao Miyoshi, Takashi Sawada, Masatoshi Fujishita, Kenji Niiya, Tomiaki Morimoto, Hirokuni Taguchi, Enzyme-linked immunosorbent assay of antibodies to adult T-cell leukemia-associated antigens. GANN Japanese Journal of Cancer Research. ,vol. 74, pp. 185- 187 ,(1983) , 10.20772/CANCERSCI1959.74.2_185
J.-B. Lepecq, C. Paoletti, A fluorescent complex between ethidium bromide and nucleic acids. Physical-chemical characterization. Journal of Molecular Biology. ,vol. 27, pp. 87- 106 ,(1967) , 10.1016/0022-2836(67)90353-1
Mitsuaki Yoshida, Mitsuhiro Osame, Hisaomi Kawai, Masami Toita, Nanako Kuwasaki, Yoshihiko Nishida, Yukako Hiraki, Kouichi Takahashi, Koichiro Nomura, Shunro Sonoda, Nobutaka Eiraku, Shinji Ijichi, Koichiro Usuku, Increased replication of HTLV-I in HTLV-I-associated myelopathy. Annals of Neurology. ,vol. 26, pp. 331- 335 ,(1989) , 10.1002/ANA.410260304
Yasuto Itoyama, Jun-ichi Kira, Naoki Fujii, Ikuo Goto, Naoki Yamamoto, Increases in helper induced T cells and activated T cells in HTLV‐I–associated myelopathy Annals of Neurology. ,vol. 26, pp. 257- 262 ,(1989) , 10.1002/ANA.410260212
Steven Jacobson, Vladimir Zaninovic, Carlos Mora, Pamela Rodgers-Johnson, William A. Sheremata, Clarence J. Gibbs, D. Carleton Gajdusek, Dale E. McFarlin, Immunological findings in neurological diseases associated with antibodies to HTLV-I: Activated lymphocytes in tropical spastic paraparesis Annals of Neurology. ,vol. 23, ,(1988) , 10.1002/ANA.410230744
Mitsuhiro Osame, Makoto Matsumoto, Koichiro Usuku, Shuji Izumo, Naomi Ijichi, Hiroyoko Amitani, Mitsutoshi Tara, Akihiro Igata, Chronic progressive myelopathy associated with elevated antibodies to human T-lymphotropic virus type I and adult T-cell leukemialike cells Annals of Neurology. ,vol. 21, pp. 117- 122 ,(1987) , 10.1002/ANA.410210203
Pamela Rodgers-Johnson, D. Carleton Gajdusek, OwenStC. Morgan, Vladimir Zaninovic, PremS. Sarin, DanielS. Graham, HTLV-I and HTLV-III antibodies and tropical spastic paraparesis. The Lancet. ,vol. 326, pp. 1247- 1248 ,(1985) , 10.1016/S0140-6736(85)90778-0
Mitsuhiro Osame, Koichiro Usuku, Shuji Izumo, Naomi Ijichi, Hiroyoko Amitani, Akihiro Igata, Makoto Matsumoto, Mitsutoshi Tara, HTLV-I ASSOCIATED MYELOPATHY, A NEW CLINICAL ENTITY The Lancet. ,vol. 327, pp. 1031- 1032 ,(1986) , 10.1016/S0140-6736(86)91298-5
Richard T. Johnson, Diane E. Griffin, Alberto Arregui, Carlos Mora, Clarence J. Gibbs, Juan M. Cuba, Luis Trelles, Abraham Vaisberg, Spastic paraparesis and HTLV-I infection in Peru. Annals of Neurology. ,vol. 23, ,(1988) , 10.1002/ANA.410230734