Aqueous Systems For The Preparation Of Lipid Based Pharmaceutical Compounds; Compositions, Methods, And Uses Thereof

作者: Moghis U. Ahmad , Ateeq Ahmad , Shoukath M. Ali , Imran Ahmad , Saifuddin Sheikh

DOI:

关键词: Aqueous solutionPolyeneTaxane derivativeOrganic chemistryChemistryActive compound

摘要: The present invention relates to a methods of preparing active compounds complexed with lipids using aqueous systems that are free organic solvents, and the complexes, e.g., in treating disease subject. In some embodiments, comprises composition comprising complex at least one compound, polyene antibiotic, an immunosuppressant agent such as tacrolimus or taxane derivative, more lipids. provides method lipid compound administering certain embodiments subject is mammal. preferred human.

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