A randomized study on the effects of estrogen/gestagen or high dose oral calcium on trabecular bone remodeling in postmenopausal osteoporosis.
作者： T. Steiniche , C. Hasling , P. Charles , E.F. Eriksen , L. Mosekilde
DOI: 10.1016/8756-3282(89)90126-9
关键词: Oral calcium 、 Elemental calcium 、 Randomized controlled trial 、 Estrogen 、 Bone remodeling 、 Calcium 、 Iliac crest 、 Trabecular bone 、 Internal medicine 、 Endocrinology 、 Medicine
摘要: Abstract Thirty-seven patients with postmenopausal crush fracture osteoporosis were randomized to oral cyclic estrogen/gestagen (n = 20) or calcium (2000 mg elemental per day) 17). Fourteen in each group completed 1 year of treatment. Iliac crest bone biopsies obtained after intravital double labeling tetracycline before and treatment 10 on 11 calcium. In the activation frequency trabecular decreased from 0.52 + 0.11 (SEM) year−1 0.27 0.08 (p
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