Comparison of an H2 Receptor Antagonist and a Neutralizing Antacid on Postprandial Acid Delivery into the Duodenum in Patients with Duodenal Ulcer

作者: Timothy B. Deering , Juan-R. Malagelada

DOI: 10.1016/S0016-5085(19)32261-9

关键词: CimetidineDuodenumHistamine H2 receptorGastroenterologyIn patientInternal medicineAntacidPostprandialTitratable acidAntagonistMedicine

摘要: Measurement of the postprandial rate acid delivery into duodenum directly assessed efficacy two radically different acid-reducing therapies for duodenal ulcer disease. Cimetidine, 400 mg, with an ordinary solid meal decreased 4-hr titratable and hydrogen ion by 63 86%, respectively (P

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