Bcl-2 proteins: regulators of apoptosis or of mitochondrial homeostasis?
作者： Matthew G. Vander Heiden , Craig B. Thompson
DOI: 10.1038/70237
关键词: Mitochondrial membrane transport protein 、 Cell biology 、 Endoplasmic reticulum 、 Biology 、 Gene 、 Mitochondrion 、 Ion channel 、 Apoptosis 、 Programmed cell death 、 Bcl-2 family
摘要: … physiology or mitochondria-dependent caspase … mitochondria in apoptosis with a consideration of how Bcl-2 proteins might control cell death through an ability to regulate mitochondrial …
nature.com
sci-hub.se 参考文章(101)
Shigemi Matsuyama, Sharon L. Schendel, Zhihua Xie, John C. Reed, Cytoprotection by Bcl-2 Requires the Pore-forming α5 and α6 Helices Journal of Biological Chemistry. ,vol. 273, pp. 30995- 31001 ,(1998) , 10.1074/JBC.273.47.30995
Kamiike W, Tsujimoto Y, Eguchi Y, Matsuda H, Shimizu S, Uchiyama Y, Waguri S, Bcl-2 blocks loss of mitochondrial membrane potential while ICE inhibitors act at a different step during inhibition of death induced by respiratory chain inhibitors. Oncogene. ,vol. 13, pp. 21- ,(1996)
W. Zhu, A. Cowie, G. W. Wasfy, L. Z. Penn, B. Leber, D. W. Andrews, Bcl-2 mutants with restricted subcellular location reveal spatially distinct pathways for apoptosis in different cell types. The EMBO Journal. ,vol. 15, pp. 4130- 4141 ,(1996) , 10.1002/J.1460-2075.1996.TB00788.X
R. S. Decker, K. Wildenthal, Lysosomal alterations in hypoxic and reoxygenated hearts. I. Ultrastructural and cytochemical changes. American Journal of Pathology. ,vol. 98, pp. 425- 444 ,(1980)
Camilla Köhler, Annie Gahm, Takafumi Noma, Atsushi Nakazawa, Sten Orrenius, Boris Zhivotovsky, Release of adenylate kinase 2 from the mitochondrial intermembrane space during apoptosis FEBS Letters. ,vol. 447, pp. 10- 12 ,(1999) , 10.1016/S0014-5793(99)00251-3
Hua Zou, Yuchen Li, Xuesong Liu, Xiaodong Wang, An APAF-1·Cytochrome c Multimeric Complex Is a Functional Apoptosome That Activates Procaspase-9 Journal of Biological Chemistry. ,vol. 274, pp. 11549- 11556 ,(1999) , 10.1074/JBC.274.17.11549
Franc PATTUS, Frederic HEITZ, Carmen MARTINEZ, Steven W. PROVENCHER, Claude LAZDUNSKI, Secondary structure of the pore-forming colicin A and its C-terminal fragment. Experimental fact and structure prediction. FEBS Journal. ,vol. 152, pp. 681- 689 ,(1985) , 10.1111/J.1432-1033.1985.TB09248.X
S. Tanaka, K. Saito, J.C. Reed, Structure-function analysis of the Bcl-2 oncoprotein. Addition of a heterologous transmembrane domain to portions of the Bcl-2 beta protein restores function as a regulator of cell survival. Journal of Biological Chemistry. ,vol. 268, pp. 10920- 10926 ,(1993) , 10.1016/S0021-9258(18)82073-7
Klaus van Leyen, Robert M. Duvoisin, Harald Engelhardt, Martin Wiedmann, A function for lipoxygenase in programmed organelle degradation Nature. ,vol. 395, pp. 392- 395 ,(1998) , 10.1038/26500
M. Nguyen, P.E. Branton, P.A. Walton, Z.N. Oltvai, S.J. Korsmeyer, G.C. Shore, Role of membrane anchor domain of Bcl-2 in suppression of apoptosis caused by E1B-defective adenovirus Journal of Biological Chemistry. ,vol. 269, pp. 16521- 16524 ,(1994) , 10.1016/S0021-9258(19)89417-6