Characteristics of cirrhosis undiagnosed during life: a comparative analysis of 73 undiagnosed cases and 149 diagnosed cases of cirrhosis, detected in 4929 consecutive autopsies.
作者： N. GRAUDAL , P. LETH , L. MÅRBJERG , A. M. GALLØE
DOI: 10.1111/J.1365-2796.1991.TB00425.X
关键词: Cause of death 、 Chi-squared distribution 、 Carcinoma 、 Medicine 、 Internal medicine 、 Cirrhosis 、 Ascites 、 Hepatocellular carcinoma 、 Autopsy 、 Varices 、 Gastroenterology
摘要: In 4929 consecutive autopsies performed during a period of 4 years, 222 cases (4.5%) cirrhosis were found, which 149 (3%) detected while the patients alive (diagnosed cirrhosis) and 73 (1.5%) not living (undiagnosed cirrhosis). Fifty-three undiagnosed appeared to be completely without signs (silent diagnosed group, 70% died from hepatic causes, in contrast 16% group. At autopsy, following complications found more frequently group than group: ascites (41% vs. 8%), oesophageal varices (44% 10%), splenomegaly (52% 29%). The prevalence hepatocellular carcinoma did differ significantly two groups (12% 8%). It is concluded that obvious occurs relatively frequently, no sensitive non-invasive screening methods are available at present.
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