Long-term results of primary total knee replacement in patients with hemophilia.

作者: Mauricio Silva , James V. Luck

DOI: 10.2106/JBJS.C.01609

关键词: Acquired immunodeficiency syndrome (AIDS)Survivorship curveCoagulopathyProsthesisEpidemiologyKnee JointOrthopedic surgeryMedicineSurgeryArthroplasty

摘要: Background: The outcome of total knee replacement in patients with hemophilia has been variable. Several authors have suggested a relationship between high rates late infection following and positive HIV status. objective this study was to evaluate the results primary replacements performed large group hemophilic at single institution by same surgeon. Methods: ninety sixty-eight 1975 2001 were reviewed retrospectively. status CD4 count time surgery recorded for fifty-three (seventy-one knees). Knee Society clinical functional scores determined twenty-nine (thirty-eight knees) who available follow-up. Prosthetic survival calculated use Kaplan-Meier survivorship analysis. Results: overall prevalence 16%. Twelve knees required removal components, reason nine them. HIV-positive HIV-negative 17% 13%, respectively (p = 0.5). When component any reason, free point, mechanical failure considered be end points, ten-year 83%, 77%, 96%, respectively. score excellent or good 80% knees, 97% knees. Conclusions: Despite anatomical challenges, is quite good. However, after high. prevention would substantially improve long-term patient population. Level Evidence: Therapeutic study, Level IV. See Instructions Authors complete description levels evidence.

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