Phylogenetic Background of Hibernation and Hibernation-Specific Proteins in Sciuridae

摘要: In mammals, hibernation is expressed in only a limited number of species, and the molecular mechanisms underlying are not well understood. We have previously demonstrated decrease hibernation-specific protein (HP) blood chipmunks during hibernation. Recently, we revealed that HP was regulated by an endogenous circannual rhythm conveys signal to brain essential for control. most mammalian hibernators other than some squirrel however, relationship between remains unknown. Here, describe phylogenetic relationships Sciuridae. The expression gene observed hibernating species. Non-hibernating species did express even though they possessed HP-20, -25, -27 genes. hibernation-associated cycle found chipmunk also occurred tree Sciuridae expressing like ground chipmunk, which belong Marmotini, diverged recently from non-hibernating HP, such as Funambulini Protoxerini. Thus, closely related evolution