T-cell development: a role for self-peptides in positive selection.

作者: Charles A Janeway

DOI: 10.1016/S0960-9822(99)80209-7

关键词: Negative selectionBiologyComputational biologyT cellPositive selectionRepertoireCellular differentiationReceptor

摘要: An important issue for immunologists is the difference between two main processes that determine mature repertoire of T-cell receptors, termed positive and negative selection. Recent papers have addressed role self-peptides in process

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