Lupus: an overview of the disease and management options.

摘要: Lupus is a chronic inflammatory autoimmune disease with wide range of clinical presentations resulting from its effect on multiple organ systems. There are four main types lupus: neonatal, discoid, drug-induced, and systemic lupus erythematosus (SLE), the type that affects majority patients. Patients experience loss self-tolerance as result abnormal immunological function production autoantibodies, which lead to formation immune complexes may adversely affect healthy tissue.Although precise etiologic mechanism unknown, genetic, hormonal, environmental factors, well abnormalities, have been identified. Associations between onset age, sex, geography, race also established. Management this should be individualized include both pharmacological nonpharmacological modalities for symptom relief resolution improved quality life.