作者: Sarah K Keadle , Steven C Moore , Joshua N Sampson , Qian Xiao , Demetrius Albanes
DOI: 10.1016/J.AMEPRE.2015.05.023
关键词: Hazard ratio 、 Medicine 、 Diabetes mellitus 、 Disease 、 Physical therapy 、 Body mass index 、 Cause of death 、 Prospective cohort study 、 Heart disease 、 Proportional hazards model 、 Internal medicine
摘要: Introduction TV viewing is the most prevalent sedentary behavior and associated with increased risk of cardiovascular disease cancer mortality, but association other leading causes death unknown. This study examined between in U.S. Methods A prospective cohort 221,426 individuals (57% male) aged 50–71 years who were free chronic at baseline (1995–1996), 93% white, an average BMI 26.7 (SD=4.4) kg/m 2 included. Participants self-reported followed until or December 31, 2011. Hazard ratios (HRs) 95% CIs for cause-specific mortality estimated using Cox proportional hazards regression. Analyses conducted 2014–2015. Results After follow-up 14.1 years, adjusted a 2-hour/day increase was significantly higher following (HR [95% CI]): (1.07 [1.03, 1.11]); heart (1.23 [1.17, 1.29]); obstructive pulmonary (1.28 [1.14, 1.43]); diabetes (1.56 [1.33, 1.83]); influenza/pneumonia (1.24 [1.02, 1.50]); Parkinson (1.35 [1.11, 1.65]); liver (1.33 [1.05, 1.67]); suicide (1.43 [1.10, 1.85]. Mortality associations persisted stratified analyses important potential confounders, reducing causation concerns. Conclusions shows breadth outcomes prolonged viewing, identifies novel several death. discretionary that may be more target public health intervention than previously recognized. Trial Registration ClinicalTrials.gov number, NCT00340015