Radiopharmaceuticals for scintigraphic imaging of infection and inflammation.

摘要: Scintigraphic imaging of infection and inflammation is a powerful diagnostic tool in the management patients with infectious or inflammatory diseases. Most foci can be visualized accurately radiolabeled autologous leukocytes. However, preparation this radiopharmaceutical laborious requires handling potentially contaminated blood. Nowadays, few radiopharmaceuticals are available that could replace leukocytes, such as: 67Ga-citrate, 99mTc-IgG 99mTc-labeled antigranulocyte antibody preparations. Furthermore, various agents labeled 99mTc currently developed for application: chemotactic peptides, cytokines liposomes. Here, characteristics potential established experimental reviewed.