Reactivation of Chagas Disease in a Patient With Follicular Lymphoma Diagnosed by Means of Quantitative Real-Time Polymerase Chain Reaction
作者： Maria I Garzón , Ariel G Sánchez , Maria C Goy , Teresita Alvarellos , Abel H Zarate
DOI: 10.1093/OFID/OFV060
关键词: Follicular lymphoma 、 Internal medicine 、 Asymptomatic 、 Medicine 、 Vincristine 、 Chagas disease 、 Gastroenterology 、 Neutropenia 、 Immunology 、 Benznidazole 、 Rituximab 、 Prednisone
摘要: We report a case of Chagas disease reactivation in patient with stage IIb follicular lymphoma the cecum. He was admitted to hospital neutropenia and fever. had history right hemicolectomy 6 months earlier received sixth cycle chemotherapy cyclophosphamide/doxorubicin/vincristine/prednisone/rituximab. Blood urine cultures were negative, but fever persisted. Reactivation confirmed by means quantitative real-time polymerase chain reaction (qRT-PCR). Parasitic load 577 950 parasite equivalents/mL. The began treatment benznidazole 5 mg/k per day every 12 hours. After 1 month, qRT-PCR control undetectable. completed 60 days is currently asymptomatic. Trypanosoma cruzi may become useful diagnostic method for disease.
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