Inner salt-shaped small molecular photosensitizer with extremely enhanced two-photon absorption for mitochondrial-targeted photodynamic therapy
作者： Wenbo Hu , Tingchao He , Rongcui Jiang , Jun Yin , Lin Li
DOI: 10.1039/C6CC09473B
关键词: Two-photon absorption 、 Photosensitizer 、 Quantum yield 、 Absorption (electromagnetic radiation) 、 Singlet oxygen 、 Biophysics 、 Chemistry 、 Molecule 、 Small molecule 、 Nanotechnology 、 Photodynamic therapy
摘要: Herein, we experimentally and theoretically demonstrate an unprecedentedly enhanced two-photon absorption in a small organic molecule by simple introduction of inner salt-shaped structure. Moreover, such also exhibits superior singlet oxygen quantum yield fascinating structure-inherent mitochondrial-targeting ability for highly efficient photodynamic therapy via mitochondrial apoptosis pathway.
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