Desulfurization of sulfur amino acids and proteins with Raney nickel
作者： M.T. Perlstein , M.Z. Atassi , S.H. Cheng
DOI: 10.1016/0005-2795(71)90162-0
关键词: Amino acid 、 Cysteine 、 Raney nickel 、 Cystine 、 Organic chemistry 、 Sodium borohydride 、 Methionine 、 Flue-gas desulfurization 、 Alanine 、 Chemistry 、 Biochemistry, Genetics and Molecular Biology (miscellaneous)
摘要: Abstract The reaction of amino acids with Raney nickel has been carefully studied and the conditions most suitable for specificity determined. Two different grades have compared. One grade was prepared by addition sodium borohydride to acetate other W 6 nickel. Reaction at pH 5.0, 7.0 8.0 40°. efficient were Cystine completely converted alanine in 4 min. No appreciable differences found rates desulfurization methionine which extremely low. At 22° or lower, showed a high degree cystine desulfurized 12 min (at 22°) while essentially unchanged even after 10 h reaction. applied specific cysteine (or cystine) residues hemoglobin, lysozyme α-lactalbumin, respectively.
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sci-hub.se 参考文章(9)
Robert E. Canfield, Peptides Derived from Tryptic Digestion of Egg White Lysozyme Journal of Biological Chemistry. ,vol. 238, pp. 2691- 2697 ,(1963) , 10.1016/S0021-9258(18)67887-1
MZ Atassi, Chemical studies on haemoglobins A1 and A0. Biochemical Journal. ,vol. 93, pp. 189- 197 ,(1964) , 10.1042/BJ0930189
M. Z. Atassi, A. F. S. A. Habeeb, Enzymic and immunochemical properties of lysozyme. I. Derivatives modified at tyrosine. Influence of nature of modification on activity. Biochemistry. ,vol. 8, pp. 1385- 1393 ,(1969) , 10.1021/BI00832A012
C.P. Ivanov, B.V. Alexiev, M. Krsteva, B. Yordanov, Determination of methionine in protein hydrolysates by reaction with raney nickel and infrared spectroscopy Analytica Chimica Acta. ,vol. 30, pp. 549- 555 ,(1964) , 10.1016/S0003-2670(00)88765-6
M.Z. Atassi, Diane J. Skalski, Immunochemistry of some artificial human hemoglobins. Immunochemistry. ,vol. 6, pp. 25- 34 ,(1969) , 10.1016/0019-2791(69)90175-X
M.Z. Atassi, A.F.S.A. Habeeb, Linea Rydstedt, Lack of immunochemical cross-reaction between lysozyme and α-lactalbumin and comparison of their conformations Biochimica et Biophysica Acta. ,vol. 200, pp. 184- 187 ,(1970) , 10.1016/0005-2795(70)90061-9
Ch. Ivanov, B. Alexiev, M. Krsteva, On the interaction of insulin with raney nickel Biochimica et Biophysica Acta. ,vol. 69, pp. 195- 197 ,(1963) , 10.1016/0006-3002(63)91250-2
Shirley Lucille Cooley, John L. Wood, Desulfurization of proteins by Raney nickel Archives of Biochemistry and Biophysics. ,vol. 34, pp. 372- 377 ,(1951) , 10.1016/0003-9861(51)90015-X
Homer Adkins, Harry R. Billica, The Preparation of Raney Nickel Catalysts and their Use Under Conditions Comparable with Those for Platinum and Palladium Catalysts Journal of the American Chemical Society. ,vol. 70, pp. 695- 698 ,(1948) , 10.1021/JA01182A080