Genetic Characterization of Atypical Shigella flexneri Isolated in Korea

作者: Sa-Hyun Hong , Yeon-Hwa Choi , Yun Choo , Young-Woon Choi , Seon-Young Choi

DOI: 10.4014/JMB.1005.05019

关键词: AmpicillinAgglutination (biology)SerologyStreptomycinTypingIntegronShigellaVirologyMicrobiologyBiologyShigella flexneriBiotechnologyApplied Microbiology and BiotechnologyGeneral Medicine

摘要: Three types of serotypically atypical Shigella flexneri isolates were collected between 2007 and 2008 from Korean patients at the Korea National Institute Health (NIH). These characterized compared with serologically typical S. flexneri. The first grouping 11 displayed agglutination only polyB antiserum exhibited no reaction any typing or sera (PolyB:un). second group 3 reactions IV, but also did not bind (IV:un). third 14 a plural pattern, reacting II, two (II:(3)4,7(8)). Amongst these isolates, belonging to IV:un II:(3)4,7(8) greater antibiotic resistance, in particular ampicillin, streptomycin, trimethoprim-sulfamethoxazole, than strains. Furthermore, all strains harbored integrons. This study suggests that multiple antibiotic-resistant are new subserotypes await further serological classification.

参考文章(21)
NI Carlin, M Rahman, David A Sack, Ansari Zaman, Bradford Kay, Alif A Lindberg, None, Use of monoclonal antibodies to type Shigella flexneri in Bangladesh. Journal of Clinical Microbiology. ,vol. 27, pp. 1163- 1166 ,(1989) , 10.1128/JCM.27.6.1163-1166.1989
F C Tenover, R D Arbeit, R V Goering, P A Mickelsen, B E Murray, D H Persing, B Swaminathan, Interpreting chromosomal DNA restriction patterns produced by pulsed-field gel electrophoresis: criteria for bacterial strain typing. Journal of clinical microbiology. ,vol. 33, pp. 2233- 2239 ,(1995) , 10.1128/JCM.33.9.2233-2239.1995
LK Siu, JYC Lo, KY Yuen, PY Chau, MH Ng, PL Ho, None, β-Lactamases in Shigella flexneri Isolates from Hong Kong and Shanghai and a Novel OXA-1-Like β-Lactamase, OXA-30 Antimicrobial Agents and Chemotherapy. ,vol. 44, pp. 2034- 2038 ,(2000) , 10.1128/AAC.44.8.2034-2038.2000
J. Y. Oh, H. S. Yu, S. K. Kim, S. Y. Seol, D. T. Cho, J. C. Lee, Changes in Patterns of Antimicrobial Susceptibility and Integron Carriage among Shigella sonnei Isolates from Southwestern Korea during Epidemic Periods Journal of Clinical Microbiology. ,vol. 41, pp. 421- 423 ,(2003) , 10.1128/JCM.41.1.421-423.2003
Myron M. Levine, Karen L. Kotloff, Eileen M. Barry, Marcela F. Pasetti, Marcelo B. Sztein, Clinical trials of Shigella vaccines: two steps forward and one step back on a long, hard road Nature Reviews Microbiology. ,vol. 5, pp. 540- 553 ,(2007) , 10.1038/NRMICRO1662
Pham thi Huan, Belinda L Whittle, David A Bastin, Alf A Lindberg, Naresh K Verma, Shigella flexneri type-specific antigen V: cloning, sequencing and characterization of the glucosyl transferase gene of temperate bacteriophage SfV. Gene. ,vol. 195, pp. 207- 216 ,(1997) , 10.1016/S0378-1119(97)00144-3
Kaisar A Talukder, Dilip K Dutta, Ashrafus Safa, M Ansaruzzaman, Ferdaus Hassan, Khorshed Alam, KMN Islam, NIA Carlin, GB Nair, David A Sack, None, Altering trends in the dominance of Shigella flexneri serotypes and emergence of serologically atypical S. flexneri strains in Dhaka, Bangladesh. Journal of Clinical Microbiology. ,vol. 39, pp. 3757- 3759 ,(2001) , 10.1128/JCM.39.10.3757-3759.2001
Jing-Cao Pan, Rong Ye, Dong-Mei Meng, Wei Zhang, Hao-Qiu Wang, Ke-Zhou Liu, Molecular characteristics of class 1 and class 2 integrons and their relationships to antibiotic resistance in clinical isolates of Shigella sonnei and Shigella flexneri Journal of Antimicrobial Chemotherapy. ,vol. 58, pp. 288- 296 ,(2006) , 10.1093/JAC/DKL228