作者: T H Maren , A B Talalay , P Wistrand , E R Swenson
DOI:
关键词: Squalus acanthias 、 Chromatography 、 Sodium 、 Acetazolamide 、 Ouabain 、 Ciliary processes 、 Aqueous solution 、 Diffusion 、 Chemistry 、 Carbonic anhydrase
摘要: Aqueous humor dynamics were studied in the dogfish, Squalus acanthias, using isotopically labeled inulin, Na+, Cl-, and HCO-3. Fluid production was 100 mul per hour, with a turnover rate constant of 0.4 hr.-1, about half that mammals. The ciliary process contains carbonic anhydrase Na-K-ATPase. Diffusion Na+ Cl- from plasma to aqueous four five times greater than flow, vitreous, 15 greater. Sodium chloride secretion is masked by diffusion process; neither ouabain nor acetazolamide yield measurable effects on accumulation these isotopes. HCO-3 very rapid reduced inhibition anhydrase. Analyses data suggest newly formed has similar concentration plasma, but high low Cl-. This anion pattern resembles mammalian humor, cerebrospinal fluid endolymph other vertebrates. These features formation fluids all phyla are sodium transport CO2.