Association of BMPR1A polymorphism, but not BMP4, with kidney size in full-term newborns.
作者： Mariusz Kaczmarczyk , Iwona Goracy , Beata Loniewska , Anna Kuprjanowicz , Agnieszka Binczak-Kuleta
DOI: 10.1007/S00467-012-2277-7
关键词: Kidney Volume 、 Nephron 、 Medicine 、 Internal medicine 、 Genetics 、 BMPR1A 、 Physiology 、 Polymorphism (computer science) 、 Gene polymorphism 、 Full Term 、 Nephrology 、 Kidney
摘要: Background A correlation between renal mass and nephron number in newborns allows the use of total kidney volume at birth as a surrogate for congenital number. As bone morphogenetic protein type 4 (BMP4), its receptor 1A (BMPR1A, ALK3), play an important role development, we hypothesized that common, functional polymorphisms their genes might be responsible variation size among healthy individuals.
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