Frequency doubling technology perimetry for detection of visual field progression in glaucoma: a pointwise linear regression analysis.

作者: Shu Liu , Marco Yu , Robert N. Weinreb , Gilda Lai , Dennis Shun-Chiu Lam

DOI: 10.1167/IOVS.13-13225

关键词: OphthalmologyLinear regressionFrequency doubling technology perimetryGlaucomaNormal groupMedicinePointwiseVisual sensitivityAutomated perimetryVisual field

摘要: PURPOSE We compared the detection of visual field progression and its rate change between standard automated perimetry (SAP) Matrix frequency doubling technology (FDTP) in glaucoma. METHODS followed prospectively 217 eyes (179 glaucoma 38 normal eyes) for SAP FDTP testing at 4-month intervals ≥36 months. Pointwise linear regression analysis was performed. A test location considered progressing when sensitivity ≤-1 dB/y nonedge ≤-2 edge locations. Three criteria were used to define an eye: ≥3 adjacent locations (conservative), any three (moderate), two (liberal) progressed. The calculated with mixed models. RESULTS Of eyes, 6.1% 3.9% progressed conservative criteria, 14.5% 5.6% moderate 20.1% 11.7% liberal by SAP, respectively. Taking all into consideration (total, 54 × 179 locations), detected more (176) than (103, P < 0.001). mean deviation (MD) significantly faster (all No showed group using criteria. CONCLUSIONS With a sensitivity, comparable level specificity. Frequency can provide useful alternative monitor progression.

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