Comparison of immune response of Pacific white shrimp, Litopenaeus vannamei, after multiple and single infections with WSSV and Vibrio anguillarum.

作者: Guo Qiao , De-Hai Xu , Zishen Wang , In-Kwon Jang , Zhitao Qi

DOI: 10.1016/J.FSI.2015.02.009

关键词: LitopenaeusToxinPathogenVirusMicrobiologyWhite spot syndromeShrimpVirologyImmune systemBiologyVibrio anguillarum

摘要: Our previous study demonstrated that Pacific white shrimp (Litopenaeus vannamei) infected by multiple pathogens showed higher mortality and death occurred more quickly than those a single pathogen (Jang et al., 2014). For better understanding the defense mechanism against spot syndrome virus (WSSV) Vibrio anguillarum, immune responses of were evaluated in this study. The mRNA expression levels five immune-related genes analyzed quantitative reverse real-time PCR, which included proPO-activating enzyme 1 (PPAE1), PPAE2, proPO activating factor (PPAF), masquerade-like serine proteinase (Mas) ras-related nuclear gene (Ran). Results transcription was suppressed intensively infection group groups. transcriptional suppression directly related to mortality. hypoimmunity could benefit invasion, replication release toxin vivo. will help understand after aquaculture.

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