Integrin Receptors and Hairy Cell Leukaemia

摘要: The ability of a cell to recognise and specifically localise within an appropriate tissue environment is essential the proliferation survival that cell. integrin family cell-surface adhesion-receptors are such localisation, allowing migrating recognise, within-, respond to- cellular or extracellular matrix ligands characterise given tissue. We have investigated how expression activity receptors underlies consistent unusual distribution malignant B lymphocytes hairy leukaemia (HCL). In this report we review our published work in area. Our findings then discussed context current knowledge their ligands, relation clinical features HCL.