Effective Management of Difficult Surgical Defects Using Tissue‐Engineered Skin

作者: Mordechai M. Tarlow , Robert Nossa , James M. Spencer

DOI: 10.1111/J.1524-4725.2001.00183.X

关键词: Surgical woundSecondary intentionHealing timeEffective managementTissue engineered skinSingle applicationSurgeryWound healingMicrographic surgeryMedicine

摘要: Background. Graftskin, a bilayered living skin construct, is an effective therapeutic option in the management of chronic venous ulcerations and simple acute surgical excisions. However, it not routinely used complicated wound defects. Objective. To determine effectiveness graftskin as modality difficult defects. Methods. Two patients with complex defects after Mohs micrographic surgery underwent single application graftskin. The engineered was fenestrated sutured place. wounds were examined on weekly basis. One hundred percent healing defined complete reepithelialization (wound coverage). Results. Graftskin well tolerated by these resulted within 9 weeks application. Conclusion. excellent alternative for amenable to other therapies. results shortened time decreased morbidity. It should be considered which secondary intention preferably avoided.

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