Experience with the use of apligraf to heal complicated surgical and nonsurgical wounds in a private practice setting.

摘要: Apligraf is supplied as a ready-to-use living fibroblast and keratinocyte bilayer in culture. This therapy has been shown to facilitate healing of venous ulcers diabetic foot ulcers. Several case reports suggest that may also be effective acute excisional wounds complicated surgical defects. can, appropriate settings, used an alternative autografts, avoiding the morbidity donor site wounds. The present review summarizes outcomes 16 patients with 18 nonsurgical treated Apligraf, which was meshed or fenestrated needed obtain better wound coverage allow drainage. Of patients, 15 (94%) experienced complete (16 wounds; 89%). Both responded well, times ranging from 21 550 days. Patients generally stated they were satisfied their degree opportunity avoid procedures associated autograft sites.