Future Directions and New Technology in Peritoneal Dialysis

作者: Michael Francis Flessner

DOI: 10.1007/978-3-642-27558-6_16

关键词: Intensive care medicinePeritoneal dialysisHealth careDialysisPeritoneal dialysis catheterPeritoneal SclerosisDesign engineerPersonalized medicineMedicine

摘要: Although peritoneal dialysis was first developed in the early 20th century, there are still many challenges that need to be addressed by bioengineers working with nephrologists. The catheter sets up a foreign body reaction cavity and often becomes infected; new polymers needed minimize resulting inflammation. New osmotic agents substitute for glucose “diabetic state” leads sclerosis. technology can worn mobile patient provides continuous is an exciting development presents significant design engineer. Computational biology attempts quantitatively integrate findings clinical studies, genomics, proteomics, metabolomics move health care toward “personalized medicine” order predict outcomes improve of individual patient.

参考文章(84)
Liping Tang, John W. Eaton, Natural Responses to Unnatural Materials: A Molecular Mechanism for Foreign Body Reactions Molecular Medicine. ,vol. 5, pp. 351- 358 ,(1999) , 10.1007/BF03402124
Newman Ka, Newman Ka, Newman Ka, Light Pd, Light Pd, Light Pd, Moody Mr, Moody Mr, Moody Mr, Reed Wp, Reed Wp, Reed Wp, Costerton Jw, Costerton Jw, Costerton Jw, Bacterial colonization of Hemasite access devices. Surgery. ,vol. 99, pp. 308- 317 ,(1986) , 10.5555/URI:PII:0039606086902503
DeVita Vt, Dedrick Rl, Myers Ce, Bungay Pm, Pharmacokinetic rationale for peritoneal drug administration in the treatment of ovarian cancer Cancer treatment reports. ,vol. 62, pp. 1- 11 ,(1978)
Gerald Cohen, Dalibor Ilic, Jana Raupachova, Walter H. Hörl, Resistin Inhibits Essential Functions of Polymorphonuclear Leukocytes Journal of Immunology. ,vol. 181, pp. 3761- 3768 ,(2008) , 10.4049/JIMMUNOL.181.6.3761
Claudio Ronco, The wearable artificial kidney: is peritoneal dialysis the solution? Contributions To Nephrology. ,vol. 163, pp. 300- 305 ,(2009) , 10.1159/000223814
Theodoros Eleftheriadis, Georgia Antoniadi, Vassilios Liakopoulos, Charalambos Kartsios, Ioannis Stefanidis, Disturbances of acquired immunity in hemodialysis patients. Seminars in Dialysis. ,vol. 20, pp. 440- 451 ,(2007) , 10.1111/J.1525-139X.2007.00283.X
Victor Gura, Masoud Beizai, Carlos Ezon, Hans-Dietrich Polaschegg, Continuous Renal Replacement Therapy for End-Stage Renal Disease Contributions To Nephrology. ,vol. 149, pp. 325- 333 ,(2005) , 10.1159/000085694
Margot N. Schilte, Paolo Fabbrini, Piet M. Ter Wee, Eelco D. Keuning, Mohammad Zareie, Geert-Jan Tangelder, Anton A. Van Lambalgen, Robert H.J. Beelen, Jacob Van Den Born, Peritoneal Dialysis Fluid Bioincompatibility and New Vessel Formation Promote Leukocyte-Endothelium Interactions in a Chronic Rat Model for Peritoneal Dialysis Microcirculation. ,vol. 17, pp. 271- 280 ,(2010) , 10.1111/J.1549-8719.2010.00024.X
Simon J. Davies, Louise Phillips, Patrick F. Naish, Gavin I. Russell, Peritoneal Glucose Exposure and Changes in Membrane Solute Transport with Time on Peritoneal Dialysis Journal of The American Society of Nephrology. ,vol. 12, pp. 1046- 1051 ,(2001) , 10.1681/ASN.V1251046
Alan S. Kliger, Frequent Nocturnal Hemodialysis—A Step Forward? JAMA. ,vol. 298, pp. 1331- 1333 ,(2007) , 10.1001/JAMA.298.11.1331