Transcriptional profiling of feline infectious peritonitis virus infection in CRFK cells and in PBMCs from FIP diagnosed cats.

作者: Mohammad Syamsul Reza Harun , Choong Oi Kuan , Gayathri Thevi Selvarajah , Tan Sheau Wei , Siti Suri Arshad

DOI: 10.1186/1743-422X-10-329

关键词: Systemic diseaseReal-time polymerase chain reactionVirologyVirusGene expression profilingBiologyFeline infectious peritonitisVirulenceCoronavirusPeripheral blood mononuclear cell

摘要: Background Feline Infectious Peritonitis (FIP) is a lethal systemic disease, caused by the FIP Virus (FIPV); virulent mutant of Feline Enteric Coronavirus (FECV). Currently, viruses virulence determinants and host gene expressions during FIPV infection are not fully understood.

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