Risk factors for in situ breast cancer.

摘要: Few data exist on risk factors for in situ breast carcinoma. We examined carcinoma from two population-based case-control studies of cancer conducted among female residents Los Angeles County. Cases with or invasive disease were identified through the registry Country 1980s. included all cases ages 40 years younger diagnosed over a 5.5-year period and 55-64 3-year period. Control subjects individually matched to by age (+/-3 years), neighborhood residence, and, controls, parity (nulliparous versus parous). The analysis 233 cancer, 2057 2203 controls. Odds ratios (ORs) 95% confidence intervals (CIs) adjusted screening mammography established factors. In general, similar those this population. premenopausal women, however, decreased increasing body mass index, whereas disease, index was unrelated risk. addition, postmenopausal women known at menopause, use unopposed estrogen replacement therapy associated increased [OR ever alone 1.60 (95% CI, 1.00-2.58)], OR 1.23 1.00-1.50). A difference seen combined hormone therapy. Unmeasured users compared nonusers could account some association use.