Patterns of care and outcomes for elderly patients with metastatic colorectal cancer in Australia

摘要: Abstract Objectives The elderly accounts for a large proportion of patients with metastatic colorectal cancer (mCRC). This study reviews patterns care and outcomes mCRC in the community setting. Materials Methods Elderly (≥ 65 years) on TRACC (Treatment Recurrent Advanced Colorectal Cancer) registry were identified. Treatment, bevacizumab-related adverse events, overall survival (OS) analysed by age cohorts, comparing those aged 65–74 vs. 75–84 ≥ 85 years correlated potential prognostic factors. Factors affecting chemotherapy bevacizumab administration using logistic regression analysis. Results Of 1439 patients, 363, 352, 106 65–74, 75–84, ≥ 85 years, respectively. 584 (71%) received first-line chemotherapy, use declining advancing (84%, 69%, 34% 65–74-, 75–84- ≥ 85-year-olds, respectively). Seven (10%) not treated basis alone. Only 10 36 very who also bevacizumab. included age, treatment location, comorbidities. There was no impact events. Resection disease occurred 173 (21%) overall, rates (26% 21% 6%). Conclusion Chemotherapy usage resection decline age. A minority are systemic therapy due to advanced Our cohort suggests underutilisation older but where given, toxicity did increase