Clinical observations in collies given ivermectin orally.

摘要: An oral liquid form of ivermectin was administered to 14 purebred Collies (12 rough coated, 2 smooth coated). All were given at dosages 100 and then 200 micrograms/kg body weight. Three the dogs developed mild clinical signs toxicosis (salivation, vomiting, confusion, ataxia, tremors) with dosage. After dosage, 7 (including 1 smooth-coated Collie) severe (seizure-like activity, recumbency, nonresponsiveness, coma). Because that not retreated, only remaining 600 micrograms/kg. Severe toxic observed in these when 2,500 Dogs supportive care while comatose state. recovered completely. The results indicated Collies) have a wide range sensitivity ivermectin-induced toxicosis.