An Environmentally Benign Catalytic Method for Versatile Synthesis of 1,4-Dihydropyridines via Multicomponent Reactions
作者： Shuo Cao , Shanshan Zhong , Changfeng Hu , Jie-Ping Wan , Chengping Wen
关键词: Catalysis 、 Organic chemistry 、 Lactic acid 、 Chemistry 、 Catalytic method
摘要: The synthesis of diverse 1,4-dihydropyridines have been achieved via the multicomponent reactions aldehydes, enaminones and amines. smoothly performed in water to provide all products with moderate excellent yields by using lactic acid as a green catalyst.
sci-hub.se 参考文章(67)
Jie-Ping Wan, Youyi Zhou, Kezhi Jiang, Hongyan Ye, Thioacetamide as an Ammonium Source for Multicomponent Synthesis of Pyridines from Aldehydes and Electron-Deficient Enamines or Alkynes Synthesis. ,vol. 46, pp. 3256- 3262 ,(2014) , 10.1055/S-0034-1378635
Peter I. Dalko, Lionel Moisan, In the Golden Age of Organocatalysis Angewandte Chemie. ,vol. 43, pp. 5138- 5175 ,(2004) , 10.1002/ANIE.200400650
David M. Stout, A. I. Meyers, Recent advances in the chemistry of dihydropyridines Chemical Reviews. ,vol. 13, pp. 223- 243 ,(1982) , 10.1021/CR00048A004
Dieter Enders, Oliver Niemeier, Alexander Henseler, Organocatalysis by N-Heterocyclic Carbenes Chemical Reviews. ,vol. 107, pp. 5606- 5655 ,(2007) , 10.1021/CR068372Z
Jie-Ping Wan, Shuo Cao, Yanfeng Jing, Copper-catalyzed homo- and cross-coupling reactions of terminal alkynes in ethyl lactate Applied Organometallic Chemistry. ,vol. 28, pp. 631- 634 ,(2014) , 10.1002/AOC.3172
Biswanath Das, Ponnaboina Thirupathi, I. Mahender, V. Saidi Reddy, Yerra Koteswara Rao, Amberlyst-15: An efficient reusable heterogeneous catalyst for the synthesis of 1,8-dioxo-octahydroxanthenes and 1,8-dioxo-decahydroacridines Journal of Molecular Catalysis A-chemical. ,vol. 247, pp. 233- 239 ,(2006) , 10.1016/J.MOLCATA.2005.11.048
Jing Sun, Guoliang Shen, Yajing Xie, Chaoguo Yan, Synthesis of Functionalized 1-Benzamido-1,4-dihydropyridines via a One-Pot Two-Step Four-Component Reaction Chinese Journal of Chemistry. ,vol. 32, pp. 1143- 1150 ,(2014) , 10.1002/CJOC.201400437
Henri Rudler, Andrée Parlier, Louis Hamon, Patrick Herson, Jean-Claude Daran, Lactonizations of carboxylic acid-substituted 3-fluorodihydropyridines with electrophiles: peculiar behaviour of F(+). Chemical Communications. pp. 4150- 4152 ,(2008) , 10.1039/B807092J
Chuanwen Sun, Yanxia Chen, Tianyan Liu, Ying Wu, Ting Fang, Jing Wang, Jiahua Xing, cis
‐Nitenpyram Analogues Containing 1,4‐Dihydropyridine: Synthesis, Insecticidal Activities, and Molecular Docking Studies Chinese Journal of Chemistry. ,vol. 30, pp. 1415- 1422 ,(2012) , 10.1002/CJOC.201200165
P. Ioan, E. Carosati, M. Micucci, G. Cruciani, F. Broccatelli, B. S. Zhorov, A. Chiarini, R. Budriesi, 1,4-Dihydropyridine Scaffold in Medicinal Chemistry, The Story so Far And Perspectives (Part 1): Action in Ion Channels and GPCRs Current Medicinal Chemistry. ,vol. 18, pp. 4901- 4922 ,(2011) , 10.2174/092986711797535173