Thioacetamide as an Ammonium Source for Multicomponent Synthesis of Pyridines from Aldehydes and Electron-Deficient Enamines or Alkynes

作者: Jie-Ping Wan , Youyi Zhou , Kezhi Jiang , Hongyan Ye

DOI: 10.1055/S-0034-1378635

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摘要: A generally applicable multicomponent method has been established for the synthesis of pyridines. In reactions, thioacetamide is used as a cheap and efficient ammonium source in reaction with aldehydes electron-deficient enamines or alkynes to give 3,4,5-trisubstituted pyridines moderate good yields high product diversity.

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