Regioselective three-component reactions of enaminones, 2-aminopyridines and enals for the synthesis of 1,2-dihydropyridines

作者: Shuo Cao , Luoting Xin , Yunyun Liu , Jie-Ping Wan , Chengping Wen

DOI: 10.1039/C5RA01901J

关键词: RegioselectivityCatalysisCombinatorial chemistryAminopyridinesChemistryOrganic chemistry

摘要: A three-component synthetic method involving the assembly of enals, N,N-disubstituted enaminones and 2-aminopyridines has been designed, which leads to facile regioselective synthesis 1,2-dihydropyridines (1,2-DHPs) with broad scope generally good yields in presence simple acid catalysts.

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