A Comparative Study of Naproxen – Beta Cyclodextrin Complexes Prepared by Conventional Methods and Using Supercritical Carbon Dioxide

作者: Susana Junco , Teresa Casimiro , Nuno Ribeiro , Manuel Nunes Da Ponte , Helena Cabral Marques

DOI: 10.1023/A:1023022008337

关键词: Carbon dioxideInorganic chemistryNuclear chemistrySolventSupercritical fluidNaproxenChemistryCyclodextrinSolubilitySupercritical carbon dioxide

摘要: Naproxen is a poorly soluble anti-inflammatorydrug, the solubility of which canbe enhanced by complexation withbeta-cyclodextrin. Besides that, the inclusioncomplex reduces the …

参考文章(3)
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JosÉ Blanco, JosÉ L. Vila-jato, Francico Otero, Soledad Anguiano, Influence of Method of Preparation on Inclusion Complexes of Naproxen with Different Cyclodextrins Drug Development and Industrial Pharmacy. ,vol. 17, pp. 943- 957 ,(1991) , 10.3109/03639049109040831